I've been doing excessive internet research and have bugged my vet to death about it, and I thought I would post here to get any info and/or advice from anyone who has had experience with this. Thanks in advance...
My 11 year old spayed lab mix has just been diagnosed with ATYPICAL CUSHINGS.
Over the past year or so she has had elevated liver enzymes, a growth by her kidney, and a few urinary infections. The vet recommended we give her SAM-e and milk thistle and just keep an eye on via regular blood work and ultrasounds. After another recent urinary infection, and higher liver enzyme levels, another ultrasound was done, which revealed that the kidney growth was larger and the liver lobes more swollen.
Last Tuesday she was cut open and biopsies of her liver and a growth near her kidney were taken. She is cancer free and the diagnosis is Atypical Cushings. Her previous Cushings test was inconclusive. It was revealed that the growth by the kidney is benign and is actually on the adrenal gland, which is causing the Cushings, which is then adversely affecting the liver.
Currently, a week post-op, her incision site is healing nicely and she is on antibiotic (Cephalexin) and pain pills (Tramadol) 3x/day each. Over the weekend she had an anal gland that almost abscessed and had to be drained and some bladder inconinence. Other than her system seeming to be completely whack from all she has had going on lately, she appears to be almost back to normal. Tail wagging, playful, greeting me when I come home from work.
That's her history and what has been going on lately. Sorry for the novel. I understand if many of you stopped reading by now. lol
The vet prescribed Trilostane (80 mg/ml) liquid solution at 1 ml once per day. She started her first dose of the med early yesterday morning (at 6 AM). This morning she threw up her breakfast (shortly before 6 AM) so I held off on giving her the Trilostane until her lunch feeding. I decided not to give her her painkiller at lunch because I don't think she is in pain anymore and I wanted to give her system a little break from so much medication. I discussed all this with her vet and we are hoping the vomit was a coincidence and not a reaction to the Trilostane. Shouldn't 24 hours be enough time for the drug to be out of her system anyway? Since I gave the Trilostane at lunch she has acted fine so far (knock on wood).
Does anyone have experience with Cushings/Trilostane/any other thing I mentioned. Any advice/help/info is much appreciated. This is my child and I want to do all I can to help her.