Genetic Disorders
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Articles > Keywords > Genetic Disorders

Genetic Disorders

Found [146] Articles :: Page 8 of 10

White-Shaker Dog Syndrome A Problem In White Dogs

Despite the rather ominous sounding name, white shaker dog syndrome is not fatal and is very rarely a serious problem for most dogs that develop the condition and are treated. As can be assumed from the name is it most commonly found in white dogs such as the Maltese, Bichon Frise, Poodle, and the West Highland White Terrier. It has also been noted in breeds that are not white in color such as the Yorkshire Terrier and the Beagle. Some all white breeds of dogs that are medium to large in size do not exhibit the condition; rather it seems to be more specific to the smaller breeds of dogs. White shaker dog syndrome is usually first noted in a puppy and young dog between the ages of six months and three years. The dogs will usually start with a slight tremor that will either stay mild in nature or become more pronounced for a period of about three to four days. Once it has reached this stage the tremor will typically stay at that intensity unless it is treated. [...]

Sub-aortic Stenosis: An Inherited Heart Defect In Some Breeds

It is always an exciting time to get a new puppy or dog, unfortunately many new owners don't consider all the possible health issues that may be associated with different breeds. In some of the medium to large breeds such as the Golden Retriever, Bullmastiff, Rottweiler, Boxer and Newfoundland the condition is considered the leading cause of heart conditions within the breed. Sub-aortic stenosis is a congenital and inherited condition, which means that it is passed on through the parents and is present when the puppy is born. What the condition actually consists of is a narrowing of the opening between the heart's left ventricle and the aorta, the major blood vessel carrying blood that is rich in oxygen to the rest of the body. The narrowing is actually caused by a thickening or the walls or a ring of scar tissue that is formed inside the aorta just at the ventricle, which will decrease the volume of blood that can be carried out of the heart to the body. [...]

Auto Immune Hemolytic Anemia (AIHA)

Immune medicated hemolytic anemia (IMHA) is the new name for Auto Immune Hemolytic Anemia (AIHA) a condition where the feline autoimmune system attacks red blood cells. The Immune System treats the red blood cells as foreign bodies; sending out antibodies which coat the red blood cells with a protein substance to single them out of the blood circulation pool for destruction. This process is called extravascular hemolysis. At the same time, the bilirubin (iron) that is extracted from these marked blood cells are sent to the liver. When this process occurs, the liver and spleen begin having problems. The spleen is overworked by having to process damaged red blood cells and enlarges as result. The liver is overloaded with bilirubin causing jaundice. [...]


Arthritis means joint inflammation, but the term is somewhat misleading because arthritis is much more than joint inflammation and cats do contract many forms of arthritis depending upon the breed and external factors. The particular forms of arthritis that cats suffer from are: Traumatic Arthritis (sprain) and Osteoarethritis, from there, there are several diseases that belong to one group or the other. Traumatic Arthritis as the name implies occurs when there is some sort of a trauma, (sprain) injury. In cats that could be the result of being hit by a moving vehicle, a cat fight, or bad fall. If the trauma is a result of a simple sprain chances are the pain will go away in no time and is really not that serious. However, if the traumatic arthritis is more serious, resulting from being hit by a car or other serious accident, a fracture may occur in the joint and your cat may require surgery to repair the damage. [...]

Asymmetrical Jaw

As we know, the bone structure that is needed in the process of chewing food is the jaw. The entire vault of the mouth is referred to as the jaw. There is an upper and lower jaw. The Maxilla is the upper jaw and the mandible is the lower jaw. Certain dogs or cats have problems with the alignment of the jaws. If the upper jaw protrudes it is called an overshot in dental terms or an overbite in layman terms. If the lower jaw protrudes it is called and undershot or under bite. Persian cats are subject to teeth and jaw problems. Since Exotic Shorthairs have much of the same genotype as the Persian and Himalayan Cat, they too will suffer from same teeth and jaw problems. These cats can have crocked teeth, sometimes the baby teeth are crooked but the adult teeth will grow in normal which is straight. [...]


Ataxia is a disease where a feline's gait, which is the way it moves, walks, runs, jumps and so on, is severely uncoordinated and the animal appears to stumble, is clumsy, wobbly, and rather odd looking. The reasons for ataxia depend upon the disease it may have contracted. It is primary a neurological disorder resulting from problems in the brain or inner ear. But can have non neurological causes as well. [h]Causes[h/] Some causes of ataxia are genetic and run in families, while others could be brought on because of a feline virus or infection, or simply by the cat's general life style. [h]Weakness[/h] A feral cat that is found starving and dehydrated or is severely anemic can become very weak and this would be a cause of ataxia. [...]

Hip Dysplasia

Hip Dysplasia refers to a deformity of the hip joint, which leads to arthritis if left untreated. This condition is very painful. Up until recently it was only large breeds of dogs that were diagnosed with hip dysplasia. Veterinarians are now realizing that all breeds of cats can have the disease as well. The Devon Rex has been reported to have a 40% likelihood of contracting the disease. The prevalence in the Main Coon Cat, Persian, and Himalayan drops down to about 20 percent and domestic housecats less than 5 percent. [h]Causes[/h] It is believed that larger breeds of cats will more often suffer from dysplasia than smaller cats. The reason for this is that the larger the bones the less protective cushioning of muscle and sinuous tissue surrounding them. Less protective cushioning leads to greater risk for hip displacement. [...]


The two reasons for the inability to hear or deafness in cats is conduction and neurological problems. Conduction anomalies are associated with the structures of the ear. The outer ear is known as the Pinna, then there is the Tympanic membrane which is the eardrum, the ear canal, and the middle ear which is also called the auditory ossicles. Neurological problems can occur in the brain, inner ear, or the auditory nerve. There is unilateral deafness implying that one ear is involved or bilateral deafness involving both ears. [...]

Ear Wax Buildup

Healthy cats will have clean ears. The inside of the ear will be pink and odor free. They will not have scratches or hair loss around the ears nor will they have ear wax buildup inside of the ear. The first acute sense in a cat is the sense of sight, while the second is sound. Their sense of sound is magnified compared to humans. A feral cat must be able to hear vermin running across the field to alert it that it is time for dinner. The sense of sound develops about the second week of life so that a baby kitten can hear its mother purring. When the inside of the ear is unhealthy it could be caused by a fungal infection or ear mites. The signs include extremely red ears, dark discharge or ear wax buildup. [...]

A Rare But Fatal Disorder: Globoid Cell Leukodystrophy

The medical condition known as Globoid Cell Leukodystrophy is also more commonly known as Krabbe's Disease. It is actually a storage disease in which the body of the dog incorrectly processes and stores the enzyme galactocerebrosidase, which is an important component in producing a chemical known as galactocerebroside. Galactocerebroside in turn is essential in the production of myelin that works in the body to coat or protect the nerve endings in the brain and spinal column. When there is not enough myelin produced to provide protection the nerves fire randomly, resulting in staggering walk, tremors and general weakness and lack of coordination in the body. [...]

Juvenile Kidney Disease Is Widespread In Many Breeds

Juvenile Kidney Disease, also known as Juvenile Renal Disease, is very common in many of the popular breeds of dogs. The list of breeds that is affected by the disease ranges from the tiny Yorkshire Terrier up to the large and giant breeds such as the Great Danes and the Irish Wolfhounds. Other breeds can include the Standard Poodle, Alaskan Malamute and the King Charles Spaniels to name just a few. It is largely believed that Juvenile Kidney Disease is somehow genetic in nature, but there are no tests or specific indicators to predetermine if a breeding male or female in any breed is carrying the gene that causes the condition. Often the biggest problems in diagnosing or correctly diagnosing Juvenile Kidney Disease is that it is wrongly grouped as part of other types of kidney diseases including renal dysplasia, which is common in many of these same breeds of dogs. The only way to completely confirm the death of the puppy or the presence of the condition of Juvenile Kidney Disease is by a biopsy of the kidney either after the second month or after the death of the puppy. [...]

Malignant Melanoma A Serious Skin Condition In Older Dogs

Some breeds of dogs, particularly those that are black or have a dark coat, are prone to melanoma, which is a form of cancer of the skin. Malignant melanoma is caused by a tumor in the melanocytes that are the cells in the skin that produce pigment or coloration. Small bumps will appear in the mouth, on the skin or between the toes and are often very fast growing. They may be black or dark brown in color and will typically have irregular, rough edges. Sometimes the tumor may stay quite small and then suddenly start to grow. The biggest concern with malignant melanoma is that the cancer quickly spreads to other organs of the body, often with fatal results. Typically the diagnosis of malignant melanoma is between the ages of 9-12 and is most common in dark colored male dogs. [...]

Vaginal Hyperplasia In Young Female Dogs

Vaginal hyperplasia is most commonly seen in young bitches of medium to large breeds and is believed to be a result of a hypersensitivity of the vaginal lining to the presence of estrogen. During the time when the female is ovulating, estrogen is released in the body and the tissues of the vagina become swollen and protrude. Often there are other symptoms such as painful urination, bleeding and the most obvious symptom will be a mass of pink colored tissue protruding from the vulva. The condition is more common in certain breeds and these include the Weimaraner, Boxer, Springer Spaniel, Mastiff, English Bulldog, St. Bernard, German Shepherd and the Labrador Retriever. Other hound breeds may also be affected by the condition. There appears to be some hereditary predisposition to the condition as lines of dogs within a breed are more prone to vaginal hyperplasia while most of the females within the breed will have no symptoms of the condition. [...]

Cysts On The Back May Be Dermoid Sinus

Dermoid sinus is a condition that occurs in several breeds but is most common in the Rhodesian Ridgeback, the Shih Tzu and the Boxer. The breed most highly affected by the condition is the Rhodesian Ridgeback, although it may also show up in mixed breeds with a history of Rhodesian Ridgeback breeding in their line. Dermoid sinus is caused by a recessive gene, which means that both the male and female must carry the gene for the condition in order for the offspring to have the condition. If any puppy in the litter is born with the condition, breeders know that both parents are carriers of the gene, even if they do not have any signs of dermoid sinus themselves. These dogs should not be bred again to prevent the possibility of producing puppies with the condition and stop puppies being born that will be carriers. It is important to note that not only should the affected puppy be neutered or spayed, but all littermates have the likelihood of being carriers so they should also be spayed or neutered and not allowed to be used in breeding programs. [...]

Osteosarcoma In Older Dogs

Osteosarcoma is a form of bone cancer that tends to be most commonly diagnosed in middle aged to senior dogs. Any breed can develop osteosarcoma but the larger heavier boned breeds tend to be the most prone to the condition. The breeds most often associated with the condition include the giant and large breeds such as the Great Dane, Newfoundland, St. Bernard, Irish Wolfhound, Rottweiler, Labrador, Golden Retriever, Boxer and Weimaranar. The group of dogs that weigh over 80 pounds are the most commonly affected, with this weight range 60% are more likely to develop the cancer than any lighter breeds of dogs. Males of any breed are more commonly diagnosed with the condition than females, perhaps because the bones tend to be heavier and more developed in males of most breeds. [...]

Found [146] Articles :: Page 8 of 10
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